CRYO-ELECTRON MICROSCOPY (CRYO-EM)

The Center for Electron Microscopy and Analysis (CEMAS) is at the forefront in the convergence of physical and life sciences. Our multidisciplinary approach drives synergy, amplifies characterization capabilities in order to challenge “what is possible” in electron microscopy, and challenges the current characterization limitations in medicine, environmental science, energy materials, and beyond.

Located in a custom designed facility, every one of our fourteen electron and ion microscopes is meeting or exceeding manufacturer performance specifications. CEMAS has recently installed a Thermo Scientific Glacios cryo-TEM with a Falcon III direct electron detector and a Ceta-D camera for MicroED analysis. In addition, CEMAS has a Thermo Scientific Krios equipped with a Bioquantum imaging filter and a K3 direct electron detector, imaging phase plates, STEM/TEM tomography and an image spherical aberration corrector.

CEMAS is able to assist users in all aspects of the cryo-EM workflow, which may include initial negative stain analysis, cryo sample preparation, grid screening, high resolution data collection, and preliminary data analysis. To get started, apply to become a CEMAS user today.

To view the Policies and Procedures for using the Cryo-Electron Microscopy facilities at CEMAS, please click here.

CRYO-EM IN THE NEWS

  • Cryo-EM capabilities on display in research aimed to combat sepsis

    Ohio State’s Center for Electron Microscopy and Analysis (CEMAS) played a role in research that may help doctors treat late-stage sepsis. Originally published by Nature Nanotechnology , the study’s findings have been highlighted by numerous media... | LEARN MORE
  • CEMAS team contributes to MRS Bulletin

    Did you pick up the December edition of MRS Bulletin? We hope you did. CEMAS Director David McComb served as a guest editor for the publication and authored a pair of articles. One of which was co-authored by Robert Williams , the assistant director... | LEARN MORE
  • Finding a new way to fight late-stage sepsis

    Researchers have developed a way to prop up a struggling immune system to enable its fight against sepsis, a deadly condition resulting from the body’s extreme reaction to infection. The scientists used nanotechnology to transform donated healthy... | LEARN MORE
  • CryoEM MicroAwards

    Cryo-Electron Microscopy (Cryo-EM) is revolutionizing structural biology and healthcare. Recent technological advances in the Cryo-EM method are helping investigators better understand human health and can lead to lifesaving developments in cancer... | LEARN MORE
  • A look inside: Cryo-EM Developments

    Cryo-Electron Microscopy has emerged as one of the most powerful and insightful methods available to biomedical researchers. For this reason, Ohio State has made a significant investment in the purchase of two new cryo-EMs located at CEMAS. The 200... | LEARN MORE
  • A better world through philanthropy and medical research

    Making the world a better place is a life goal shared by most. And we can all contribute in ways large and small. Chemical engineering alumnus Tom Claugus and partner Beatriz Illescas Putzeys are going big. An Ohio native, Tom earned his BS in Chemical... | LEARN MORE
  • Exciting Cryo-EM Updates

    The rapidly advancing field of Cryo-Electron Microscopy (Cryo-EM) continues to generate many new and exciting molecular structures that have never been seen before. These structures contain many important details about protein function and may hold... | LEARN MORE
  • A cool way to accelerate Ohio State life science research

    Cryo-electron microscopy is coming to The Ohio State University. And it should deliver immediate benefits to Ohio State’s medical research enterprise once installation of the complex equipment is completed in the spring. Earlier this month, the... | LEARN MORE

Become a CEMAS User

Are you interested in gaining access to our state-of-the-art instruments and expertise? Take the next step toward becoming a CEMAS user.