CRYO-ELECTRON MICROSCOPY (CRYO-EM)
 

CEMAS is at the forefront in the convergence of physical and life sciences. Our multidisciplinary approach drives synergy and amplifies characterization capabilities to challenge "what is possible" in electron microscopy. Our comprehensive cryo-electron microscopy (cryo-EM) program advances this effort.

Located in a custom-designed facility, all electron and ion microscopes at CEMAS meet or exceed manufacturer performance specifications. CEMAS recently installed a Thermo Scientific Glacios Cryo-TEM with a Falcon III direct electron detector and a Ceta-D camera for MicroED analysis. In addition, CEMAS has a Thermo Scientific Krios G3i Cryo-TEM equipped with a Bioquantum imaging filter and a K3 direct electron detector, imaging phase plates, STEM/TEM tomography, and an image spherical aberration corrector. 

CEMAS can assist users in all aspects of the cryo-EM workflow, including initial negative stain analysis, cryogenic sample preparation, grid screening, high-resolution data collection, and preliminary data analysis.

To get started, apply to become a CEMAS user. To view the Policies and Procedures for using the Cryo-Electron Microscopy facilities at CEMAS, please click here.

double-arrowCyro-EM Instruments at CEMAS

In late 2018, CEMAS installed the Thermo Glacios cryoEM, which has a 200 kV x-FEG source and can be configured for single particle analysis (SPA), tomography, and other applications. Its capabilities include sample screening and data acquisition, maximum throughput, direct electron detection...
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In the spring of 2019, CEMAS installed the Thermo Scientific Krios G3i cryoEM which has a 300 kV x-FEG source and can be configured for single particle analysis (SPA), tomography, and other applications.
Learn More

double-arrowCyro-EM Techniques

Cryo-Electron Tomography

Single Particle Analysis

Micro Electron Diffraction

CRYO-EM INSTRUMENT MANAGERS

CRYO-EM RESOURCES